The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2012
Filed:
Sep. 23, 2008
Applicants:
Yves Guminski, Lagarrigue, FR;
Martial Grousseaud, Castres, FR;
Thierry Imbert, Viviers les Montagnes, FR;
Inventors:
Yves Guminski, Lagarrigue, FR;
Martial Grousseaud, Castres, FR;
Thierry Imbert, Viviers les Montagnes, FR;
Assignee:
Pierre Fabre Medicament, Boulogne Billancourt, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/77 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention describes a new process for the preparation of (poly)aminoalkylaminoacetamide compounds of epipodophyllotoxin useful for their applications in therapeutics as anticancer agents. This process comprises a step of condensation of a primary-amine-containing reactant, whose amine functions are not protected, with β-chloroacetamido-4'-epipodophyllotoxin in a polar aprotic organic solvent.