The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2012
Filed:
Dec. 08, 2006
Seong Eon Ryu, Taejeon-si, KR;
Seung Jun Kim, Taejeon-si, KR;
Dae Gwin Jeong, Taejeon-si, KR;
Sang Hyeup Lee, Taejeon-si, KR;
Suk Kyeong Jung, Taejeon-si, KR;
Hwan Mook Kim, Taejeon-si, KR;
Song Kyu Park, Taejeon-si, KR;
Ki Ho Lee, Seoul, KR;
Chang Woo Lee, Taejeon-si, KR;
Joong-kwon Choi, Taejeon-si, KR;
Jin Hee Ahn, Taejeon-si, KR;
Seong Eon Ryu, Taejeon-si, KR;
Seung Jun Kim, Taejeon-si, KR;
Dae Gwin Jeong, Taejeon-si, KR;
Sang Hyeup Lee, Taejeon-si, KR;
Suk Kyeong Jung, Taejeon-si, KR;
Hwan Mook Kim, Taejeon-si, KR;
Song Kyu Park, Taejeon-si, KR;
Ki Ho Lee, Seoul, KR;
Chang Woo Lee, Taejeon-si, KR;
Joong-Kwon Choi, Taejeon-si, KR;
Jin Hee Ahn, Taejeon-si, KR;
Korea Research Institute of Bioscience and Biotechnology, Taejeon-Si, KR;
Abstract
Disclosed herein are rhodanine derivatives, a method for the preparation thereof, and a pharmaceutical composition containing the same. The rhodanine derivatives have inhibitory activity against protein phosphatases (PPase) such as PTP1B, Prl-3, LAR, CD45, Cdc25A, Cdc25B, Cdc25C, Yop, PP1 and VHR, and can be applied for the prevention and treatment of PPase-caused diseases, including autoimmune diseases, diabetes, impaired glucose intolerance, insulin resistance, obesity, cancers, etc. when the inhibitory activity thereof is modulated.