The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2012

Filed:

Oct. 23, 2007
Applicants:

Gulzar Ahmed, Voorhees, NJ (US);

Henry Joseph Breslin, Lansdale, PA (US);

Jason Burke, Charlottesville, VA (US);

Matthew A. Curry, Coatesville, PA (US);

James L. Diebold, Eagleville, PA (US);

Bruce Dorsey, Ambler, PA (US);

Benjamin J. Dugan, Glen Mills, PA (US);

Daming Feng, East Windsor, NJ (US);

Diane E. Gingrich, Downingtown, PA (US);

Tao Guo, Dayton, NJ (US);

Keith S. Learn, Perkiomenville, PA (US);

Joseph G. Lisko, Glenmoore, PA (US);

Rong-qiang Liu, Kendall Park, NJ (US);

Eugen Florin Mesaros, Philadelphia, PA (US);

Karen Milkiewicz, Exton, PA (US);

Gregory R. Ott, Media, PA (US);

Jay P. Theroff, West Chester, PA (US);

Tho V. Thieu, Ambler, PA (US);

Rabindranath Tripathy, Churchville, PA (US);

Theodore L. Underiner, Malvern, PA (US);

Gregory J. Wells, West Chester, PA (US);

Craig A. Zificsak, Downingtown, PA (US);

Inventors:

Gulzar Ahmed, Voorhees, NJ (US);

Henry Joseph Breslin, Lansdale, PA (US);

Jason Burke, Charlottesville, VA (US);

Matthew A. Curry, Coatesville, PA (US);

James L. Diebold, Eagleville, PA (US);

Bruce Dorsey, Ambler, PA (US);

Benjamin J. Dugan, Glen Mills, PA (US);

Daming Feng, East Windsor, NJ (US);

Diane E. Gingrich, Downingtown, PA (US);

Tao Guo, Dayton, NJ (US);

Keith S. Learn, Perkiomenville, PA (US);

Joseph G. Lisko, Glenmoore, PA (US);

Rong-Qiang Liu, Kendall Park, NJ (US);

Eugen Florin Mesaros, Philadelphia, PA (US);

Karen Milkiewicz, Exton, PA (US);

Gregory R. Ott, Media, PA (US);

Jay P. Theroff, West Chester, PA (US);

Tho V. Thieu, Ambler, PA (US);

Rabindranath Tripathy, Churchville, PA (US);

Theodore L. Underiner, Malvern, PA (US);

Gregory J. Wells, West Chester, PA (US);

Craig A. Zificsak, Downingtown, PA (US);

Assignee:

Cephalon, Inc., Frazer, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); C07D 239/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a compound of formula I or II or a pharmaceutically acceptable salt form thereof, wherein R, R, R, R, R, A, A, A, A, and A, are as defined herein. The compounds of formula I or II have ALK and/or c-Met inhibitory activity, and may be used to treat proliferative disorders.


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