The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2012
Filed:
Nov. 24, 2008
Jae Young Yu, Kyunggi-do, KR;
Seul Min Choi, Kyunggi-do, KR;
Kyung Koo Kang, Kyunggi-do, KR;
Byoung OK Ahn, Kyunggi-do, KR;
Moohi Yoo, Seoul, KR;
Jae Young Yu, Kyunggi-do, KR;
Seul Min Choi, Kyunggi-do, KR;
Kyung Koo Kang, Kyunggi-do, KR;
Byoung Ok Ahn, Kyunggi-do, KR;
Moohi Yoo, Seoul, KR;
Dong-A Pharmtech Co., Ltd., Seoul, KR;
Abstract
The present invention relates to an agent for preventing and treating benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) associated with BPH and a relaxant for relaxing urethral smooth muscle or prostatic smooth muscle comprising a pyrazolopyrimidinone compound as an effective ingredient. The agent in accordance with the present invention can provide nitric oxides by inhibiting the activity of PDE-5 that decomposes c-GMP, and the provided nitric oxides relax the urethral smooth muscle or the prostatic smooth muscle to lower the intraurethral pressure (IUP), thus treating BPH and LUTS associated with BPH. Furthermore, the time required for reaching a maximum blood concentration is shorter and the half-life is longer than the other PDE-5 inhibitors, thus reducing the frequency of administration. Moreover, the agent of the invention causing few side effects can be efficiently used as a safe drug.