The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2012

Filed:

May. 16, 2008
Applicants:

Nathalie Chereze, Paris, FR;

Alistair Lochead, Paris, FR;

Mourad Saady, Paris, FR;

Franck Slowinski, Paris, FR;

Philippe Yaiche, Paris, FR;

Inventors:

Nathalie Chereze, Paris, FR;

Alistair Lochead, Paris, FR;

Mourad Saady, Paris, FR;

Franck Slowinski, Paris, FR;

Philippe Yaiche, Paris, FR;

Assignees:

Sanofi-Aventis, Paris, FR;

Mitsubishi Tanabe Pharma Corporation, Osaka-Shi, Osaka, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 239/00 (2006.01); C07D 223/00 (2006.01); A61K 31/55 (2006.01); A61K 31/519 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
Abstract

A pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: Wherein Y, Z, R1, R2, R3, R4, R5, R6, R7, n, m, and o are as described herein. The invention relates also to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3β, such as Alzheimer disease.


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