The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2012
Filed:
Dec. 14, 2007
Malte Meppen, Rome, IT;
Frank Narjes, Rome, IT;
Barbara Pacini, Rome, IT;
Cristina Gardelli, Rome, IT;
Philippe L. Durette, New Providence, NJ (US);
Malte Meppen, Rome, IT;
Frank Narjes, Rome, IT;
Barbara Pacini, Rome, IT;
Cristina Gardelli, Rome, IT;
Philippe L. Durette, New Providence, NJ (US);
Istituto di Ricerche di Biologia Molecolare P. Angeletti S.P.A., Rome, IT;
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention provides nucleoside cyclic phosphoramidates of formula (I), pharmaceutical compositions comprising the compounds of formula (I) and methods of inhibiting RNA-dependent RNA polymerase, inhibiting RNA-dependent RNA viral replication, and/or treating RNA-dependent RNA viral infection using the compounds of formula (I).