The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2012
Filed:
Mar. 26, 2009
Akin Akinc, Needham, MA (US);
Tomoko Nakayama, Cambridge, MA (US);
David Konys, Natick, MA (US);
Markus Stoffel, Zurich, CH;
Christian Wolfrum, Zurich, CH;
Akin Akinc, Needham, MA (US);
Tomoko Nakayama, Cambridge, MA (US);
David Konys, Natick, MA (US);
Markus Stoffel, Zurich, CH;
Christian Wolfrum, Zurich, CH;
Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);
ETH Zurich, Zurich, CH;
Abstract
This invention relates to new formulated lipid particles (FLiPs) comprising at least one of a single or double stranded oligonucleotide, where the oligonucleotide has been conjugated to a lipophile and at least one of an emulsion or liposome to which the conjugated oligonucleotide has been aggregated, admixed or associated. These particles have surprisingly been shown to effectively deliver oligonucleotides to heart, lung and muscle where they effect gene silencing.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile