The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2012
Filed:
Jun. 30, 2006
Ann-kristin Spiik, Tullinge, SE;
Robert Löfberg, Stockholm, SE;
Lisa Charlotta Bandholtz, Stockholm, SE;
Oliver Von Stein, Upplands Väsby, SE;
Ann-Kristin Spiik, Tullinge, SE;
Robert Löfberg, Stockholm, SE;
Lisa Charlotta Bandholtz, Stockholm, SE;
Oliver Von Stein, Upplands Väsby, SE;
InDex Pharmaceuticals AB, Stockholm, SE;
Abstract
The present invention makes it possible to enhance steroid efficacy in a steroid refractory patient afflicted with an inflammatory condition not responding or responding poorly or inadequately to anti-inflammatory treatment, by administering an effective amount of an oligonucleotide having the sequence 5'-Xm-TTCGT-Yn-3′ to 5 said patient, wherein X is A, T, C or G, Y is A, T, C or G, m=0-7, n=0-7 and wherein at least one CG dinucleotide is unmethylated. The invention also encompasses the use of said oligonucleotide for the manufacture of pharmaceuticals.