The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2012

Filed:

Apr. 21, 2011
Applicants:

Douglas T. Gjerde, Saratoga, CA (US);

Ronald Jones, Morgan Hill, CA (US);

Allen Burge, Sunnyvale, CA (US);

Inventors:

Douglas T. Gjerde, Saratoga, CA (US);

Ronald Jones, Morgan Hill, CA (US);

Allen Burge, Sunnyvale, CA (US);

Assignee:

PhyNexus, Inc., San Jose, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/18 (2006.01); G01N 30/02 (2006.01); B01D 15/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a bed of extraction media positioned in the column between two frits. In some embodiments, the extraction columns employ modified pipette tips as column bodies. In some embodiments, the method involves adjusting the head pressure of the column during the process, or otherwise controlling or regulating the head pressure.


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