The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2012

Filed:

Mar. 18, 1999
Applicants:

John Hermon-taylor, London, GB;

Timothy John Bull, London, GB;

Inventors:

John Hermon-Taylor, London, GB;

Timothy John Bull, London, GB;

Assignee:

HAV Vaccines Limited, London, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C07H 21/02 (2006.01); C12N 1/12 (2006.01); C12N 1/20 (2006.01); C12N 15/00 (2006.01); A01N 63/00 (2006.01); A01N 65/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to the protein,acylase (mpa) and the gene encoding mpa, which we have identified in the pathogenMptb (also designatedsubspeciesMAP), and to their use in the diagnosis of Mptb/MAP infections in animals and humans, as well as their use as components of vaccines for the prevention and treatment of diseases caused by Mptb/MAP. The importance of an intact uninterrupted mpa gene as a determinant of pathogenicity in Mptb/MAP is recognized and the invention also provides attenuated strains of normally pathogenic Mptb/MAP and other mycobacteria in which mpa has been inactivated, for use as vaccines.


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