The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2012
Filed:
Feb. 14, 2006
Shin-ichiro Nishimura, Sapporo, JP;
Noriko Nagahori, Sapporo, JP;
Tomoki Hamamoto, Choshi, JP;
Kiyoshi Okuyama, Choshi, JP;
Toshitada Noguchi, Choshi, JP;
Shin-Ichiro Nishimura, Sapporo, JP;
Noriko Nagahori, Sapporo, JP;
Tomoki Hamamoto, Choshi, JP;
Kiyoshi Okuyama, Choshi, JP;
Toshitada Noguchi, Choshi, JP;
National University Corporation Hokkaido University, Sapporo-shi, JP;
Yamasa Corporation, Choshi-shi, JP;
Abstract
The present invention is directed to, for example, an oligosaccharide having at an end thereof a 4-position halogenated galactose residue represented by formula (I): (wherein X represents a halogen atom, and R represents a monosaccharide, an oligosaccharide, or a carrier), a transferase inhibitor containing the oligosaccharide, and a method for inhibiting sugar chain elongation reaction in the presence of glycosyltransferase, the method including employing the inhibitor. The invention also provides a method for producing a 4-position halogenated galactose sugar nucleotide represented by formula (II): (wherein each of Rto Rrepresents a hydroxyl group, an acetyl group, a halogen atom, or a hydrogen atom; X represents a halogen atom; and M represents a hydrogen ion or a metal ion), wherein the method employs bacterium-derived galactokinase and bacterium-derived hexose-1-phosphate uridylyltransferase. The invention is also directed to a sugar chain containing 4-position halogenated galactose envisaged to be employed as drugs and other materials, and to applications of the compound.