The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2012

Filed:

Jan. 05, 2011
Applicants:

Priscilla Reyes, Duncan, OK (US);

William F. Moore, Bloominton, IN (US);

Patrick H. Ruane, San Mateo, CA (US);

Darin G. Schaeffer, Bloomington, IN (US);

Melinda S. Morrell, Vienna, VA (US);

Inventors:

Priscilla Reyes, Duncan, OK (US);

William F. Moore, Bloominton, IN (US);

Patrick H. Ruane, San Mateo, CA (US);

Darin G. Schaeffer, Bloomington, IN (US);

Melinda S. Morrell, Vienna, VA (US);

Assignee:

Cook Medical Technologies LLC, Bloomington, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F 2/82 (2006.01); A61F 2/00 (2006.01); A61K 31/335 (2006.01); A61M 25/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

This disclosure relates to implantable medical devices coated with a taxane therapeutic agent, such as paclitaxel, in one or more solid form(s) having varying dissolution rates. Particularly preferred coatings comprise amorphous and/or solvated solid forms of taxane therapeutic agents that provide durable coatings that release the taxane over a desired period of time, which can be varied in the absence of a polymer by selecting the type and amount of solid forms of the taxane therapeutic agent in the coating. Other preferred embodiments relate to methods of coating medical devices and methods of treatment. The coatings can provide a sustained release of the taxane therapeutic agent within a body vessel without containing a polymer to achieve the desired rate of paclitaxel elution.


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