The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 2012

Filed:

Jun. 08, 2009
Applicants:

Mark A. Gallop, Santa Clara, CA (US);

Jia-ning Xiang, Palo Alto, CA (US);

Fenmei Yao, Mountain View, CA (US);

Laxminarayan Bhat, Santa Clara, CA (US);

Cindy X. Zhou, Palo Alto, CA (US);

Inventors:

Mark A. Gallop, Santa Clara, CA (US);

Jia-Ning Xiang, Palo Alto, CA (US);

Fenmei Yao, Mountain View, CA (US);

Laxminarayan Bhat, Santa Clara, CA (US);

Cindy X. Zhou, Palo Alto, CA (US);

Assignee:

XenoPort, Inc., Santa Clara, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 271/12 (2006.01); A61K 31/27 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a method for synthesizing 1-(acyloxy)-alkyl derivatives from 1-acyl-alkyl derivatives, which typically proceeds stereospecifically, in high yield, does not require the use of activated intermediates and/or toxic compounds and is readily amendable to scale-up. The current invention also provides 1-acyl-alkyl derivatives of known drug components and methods for synthesizing these 1-acyl-alkyl derivatives.


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