The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2012
Filed:
May. 23, 2008
Applicants:
Luca Parlanti, New York, NY (US);
Jurong Yu, Dayton, NJ (US);
Inventors:
Luca Parlanti, New York, NY (US);
Jurong Yu, Dayton, NJ (US);
Assignee:
Bristol-Myers Squibb Company, Princeton, NJ (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 417/00 (2006.01); C07D 277/20 (2006.01); C07D 277/30 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process for making epi-epothilone compounds according to formula A.1, by reacting a compound according formula C with at least one halogenating agent followed by treatment with base, where R, R, R, R, R, R, R, R, Zand Zin formulae (A.1) and (C) are as defined herein. The epi-epothilone compounds of formula (A.1) can be converted into aziridinyl epothilone compounds, which are useful for the treatment of cancer.