The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2012
Filed:
Jan. 07, 2010
Henning Steinhagen, Frankfurt am Main, DE;
Hauke Szillat, Frankfurt am Main, DE;
Markus Follmann, Wülfrath, DE;
Reinhard Kirsch, Frankfurt am Main, DE;
Volkmar Wehner, Frankfurt am Main, DE;
Hans Matter, Frankfurt am Main, DE;
Martin Lorenz, Frankfurt am Main, DE;
Kent W. Neuenschwander, Bridgewater, NJ (US);
Anthony C. Scotese, Bridgewater, NJ (US);
Henning Steinhagen, Frankfurt am Main, DE;
Hauke Szillat, Frankfurt am Main, DE;
Markus Follmann, Wülfrath, DE;
Reinhard Kirsch, Frankfurt am Main, DE;
Volkmar Wehner, Frankfurt am Main, DE;
Hans Matter, Frankfurt am Main, DE;
Martin Lorenz, Frankfurt am Main, DE;
Kent W. Neuenschwander, Bridgewater, NJ (US);
Anthony C. Scotese, Bridgewater, NJ (US);
Sanofi-Aventis, Paris, FR;
Abstract
The present invention relates to compounds of formula I, The compounds of formula I are valuable pharmacologically active compounds. They exhibit a strong anti-thrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardio-vascular disorders like thromboembolic diseases or restenoses. They are inhibitors of the blood clotting enzymes, especially factor VIIa and can in general be applied in conditions in which an undesired activity of factor VIIa is present or for the cure or prevention of which an inhibition of factor VIIa is intended. The invention furthermore relates to processes for the preparation of compounds of formula I, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.