The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2012
Filed:
Feb. 28, 2011
Rémy Griffais, Montrouge, FR;
Susan K. Hoiseth, Fairport, NY (US);
Robert J. Zagursky, Victor, NY (US);
Benjamin J. Metcalf, Rochester, NY (US);
Joel A. Peek, Pittsford, NY (US);
Banumathi Sankaran, Penfield, NY (US);
Leah D. Fletcher, Geneseo, NY (US);
Rémy Griffais, Montrouge, FR;
Susan K. Hoiseth, Fairport, NY (US);
Robert J. Zagursky, Victor, NY (US);
Benjamin J. Metcalf, Rochester, NY (US);
Joel A. Peek, Pittsford, NY (US);
Banumathi Sankaran, Penfield, NY (US);
Leah D. Fletcher, Geneseo, NY (US);
Merck Serono Biodevelopment, Lyons, FR;
Abstract
The subject of the invention is the genomic sequence and the nucleotide sequences encoding polypeptides of, such as cellular envelope polypeptides, which are secreted or specific, or which are involved in metabolism, in the replication process or in virulence, polypeptides encoded by such sequences, as well as vectors including the said sequences and cells or animals transformed with these vectors. The invention also relates to transcriptional gene products of thegenome, such as, for example, antisense and ribozyme molecules, which can be used to control growth of the microorganism. The invention also relates to methods of detecting these nucleic acids or polypeptides and kits for diagnosinginfection. The invention also relates to a method of selecting compounds capable of modulating bacterial infection and a method for the biosynthesis or biodegradation of molecules of interest using the said nucleotide sequences or the said polypeptides. The invention finally comprises, pharmaceutical, in particular vaccine, compositions for the prevention and/or treatment of bacterial, in particular, infections.