The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2012
Filed:
Sep. 29, 2006
Jun-ichi Tanabe, Kanagawa, JP;
Saburo Sone, Kanagawa, JP;
Takaji Wakita, Tokyo, JP;
Koji Ishii, Tokyo, JP;
Ryosuke Suzuki, Chiba, JP;
Tetsuro Suzuki, Tokyo, JP;
Tatsuo Miyamura, Tokyo, JP;
Jun-ichi Tanabe, Kanagawa, JP;
Saburo Sone, Kanagawa, JP;
Takaji Wakita, Tokyo, JP;
Koji Ishii, Tokyo, JP;
Ryosuke Suzuki, Chiba, JP;
Tetsuro Suzuki, Tokyo, JP;
Tatsuo Miyamura, Tokyo, JP;
Tokyo Metropolitan Institute of Medical Science, Tokyo, JP;
Abstract
The present invention relates to a method for producing infectious hepatitis C virus (HCV) particles, comprising a step of introducing an expression vector into a cell that allows HCV proliferation, such expression vector comprising: DNA sequences encoding the 5' untranslated region, structural proteins, and, if necessary, non-structural proteins of HCV and DNA sequences encoding non-structural proteins and the 3′ untranslated region derived from the HCV JFH1 strain, which are located downstream of a polymerase I promoter; and a DNA fragment containing an RNA polymerase I terminator, which is located further downstream thereof.