The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2012
Filed:
Jan. 21, 2009
Achim Müller, Grossostheim, DE;
Monika Knuth, Aschaffenburg, DE;
Ralf Pasternack, Griesheim, DE;
Jens Zotzel, Darmstadt, DE;
Christine Reiff, Lörrach, DE;
Achim Müller, Grossostheim, DE;
Monika Knuth, Aschaffenburg, DE;
Ralf Pasternack, Griesheim, DE;
Jens Zotzel, Darmstadt, DE;
Christine Reiff, Lörrach, DE;
Novartis AG, Basel, CH;
Abstract
The invention relates to a process for producing biomedical articles, in particular, silicone hydrogel contact lenses having durable hydrophilic chitosan coating. The chitosan coating is covalently attached to the medical device by performing a crosslinking reaction between chitosan and the carboxylic groups on the surface of a medical device directly in a sealed package during autoclave. The coated biomedical articles obtainable by the process of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus especially useful in the field of ophthalmic devices.