The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2012
Filed:
Nov. 23, 2007
Volker Schirrmacher, Heidelberg, DE;
Philipp Beckhove, Heidelberg, DE;
Philippe Fournier, Edingen, DE;
Maximilian Aigner, Germering, DE;
Volker Schirrmacher, Heidelberg, DE;
Philipp Beckhove, Heidelberg, DE;
Philippe Fournier, Edingen, DE;
Maximilian Aigner, Germering, DE;
Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts, Heidelberg, DE;
Abstract
The present invention relates to an antibody fusion protein which specifically recognizes the VA, HN or F surface antigen of the New Castle Disease Virus (NDV), a surface molecule of a tumor-unspecific T cell or a surface molecule of a dendritic cell and an immunocytokine. Also encompassed by the present invention are polynucleotides encoding the aforementioned antibody fusion protein as well as tumor-unspecific key cells or dendritic cells bound by the antibody fusion protein. Moreover, the present invention relates to a method of treating a tumor in a subject comprising administering to the said subject the antibody fusion protein, the tumor-unspecific T cell, the dendritic cell or the polynucleotide of the invention. Preferably, the said tumor is a solid tumor.