The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 20, 2012

Filed:

Dec. 02, 2008
Applicants:

Ali Khamene, Princeton, NJ (US);

Tina Ehtiati, Baltimore, MD (US);

John V. Frangioni, Wayland, MA (US);

Vida Kianzad, Newton, MA (US);

Fred S. Azar, Princeton, NJ (US);

Inventors:

Ali Khamene, Princeton, NJ (US);

Tina Ehtiati, Baltimore, MD (US);

John V. Frangioni, Wayland, MA (US);

Vida Kianzad, Newton, MA (US);

Fred S. Azar, Princeton, NJ (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G06K 9/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for unsupervised classification of histological images of prostatic tissue includes providing histological image data obtained from a slide simultaneously co-stained with NIR fluorescent and Hematoxylin-and-Eosin (H&E) stains, segmenting prostate gland units in the image data, forming feature vectors by computing discriminating attributes of the segmented gland units, and using the feature vectors to train a multi-class classifier, where the classifier classifies prostatic tissue into benign, prostatic intraepithelial neoplasia (PIN), and Gleason scale adenocarcinoma grades 1 to 5 categories.


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