The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 20, 2012

Filed:

Jul. 26, 2005
Applicants:

Yukihiko Hara, Tokyo, JP;

Hiroshi Hojo, Shizuoka, JP;

Slobodan Jovanovic, Nepean, CA;

Inventors:

Yukihiko Hara, Tokyo, JP;

Hiroshi Hojo, Shizuoka, JP;

Slobodan Jovanovic, Nepean, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 311/62 (2006.01); C07F 9/50 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compositions and methods are directed to covalent adducts between reducing agents and optionally substituted 3-hydroxyflavans, wherein the reducing agent is covalently bound to the B-ring of the 3-hydroxyflavan. Such adducts exhibit markedly increased stability towards oxidation as compared to the unmodified 3-hydroxyflavan. Particularly preferred 3-hydroxyflavans include green tea catechins, and especially EGCG, while especially preferred reducing agents include NAC and glutathione.


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