The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2012
Filed:
Jan. 22, 2007
Applicants:
Murat Acemoglu, Basel, CH;
Sabine Pfeffer, Weil am Rhein, DE;
Inventors:
Murat Acemoglu, Basel, CH;
Sabine Pfeffer, Weil am Rhein, DE;
Assignee:
Novartis AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/16 (2006.01); C07D 498/16 (2006.01); A61K 31/436 (2006.01);
U.S. Cl.
CPC ...
Abstract
Processes for the production of a 32-deoxorapamycin from a 32-iodo- or 32-hydroxyrapamycin, wherein the hydroxy group is substituted by the residue of an arylthionocarbonate or an arylthiocarbamate, in the presence of tris(trimethylsilyl)-silan and α,α'-azo-isobutyronitril in organic solvent; and 32-deoxorapamycin in the form of a crystalline solvate.