The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2012
Filed:
May. 29, 2006
Shiho Ishikawa, Ushiku, JP;
Tsuyoshi Nagase, Tsukkuba, JP;
Nagaaki Sato, Tsukkuba, JP;
Hidekazu Takahashi, Tsukuba, JP;
Shigeru Tokita, Tsukkuba, JP;
Toshihiro Wada, Osaka, JP;
Shiho Ishikawa, Ushiku, JP;
Tsuyoshi Nagase, Tsukkuba, JP;
Nagaaki Sato, Tsukkuba, JP;
Hidekazu Takahashi, Tsukuba, JP;
Shigeru Tokita, Tsukkuba, JP;
Toshihiro Wada, Osaka, JP;
MSD. K.K., Chiyoda-Ku, JP;
Abstract
Disclosed is a substance having an antagonistic effect on the binding of histamine to a histamine H3 receptor or an inhibitory effect on the activity which a histamine H3 receptor constantly exhibits. A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof; (I) wherein R1 represents a phenyl group which may be substituted or the like and R2 represents a cyano group which may be substituted or the like, or R1 and R2 together form an aliphatic heterocylic ring which may be substituted; R3 represents a group represented by the formula (II-1) below; and all of X1 to X4 represent a carbon atom or the like: (II-1) where R4 and R5 represent a lower alkyl group or the like; and m1 represents an integer of 2 to 4.