The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2012
Filed:
Jan. 08, 2008
Tomoharu Iino, Tsukuba, JP;
Hideki Jona, Moriya, JP;
Hideki Kurihara, Tsukuba, JP;
Masayuki Nakamura, Tsukuba, JP;
Kenji Niiyama, Tsuchiura, JP;
Jun Shibata, Tsukuba, JP;
Tadashi Shimamura, Tsukuba, JP;
Hitomi Watanabe, Tsukuba, JP;
Takeru Yamakawa, Tsukuba, JP;
Lihu Yang, Edison, NJ (US);
Tomoharu Iino, Tsukuba, JP;
Hideki Jona, Moriya, JP;
Hideki Kurihara, Tsukuba, JP;
Masayuki Nakamura, Tsukuba, JP;
Kenji Niiyama, Tsuchiura, JP;
Jun Shibata, Tsukuba, JP;
Tadashi Shimamura, Tsukuba, JP;
Hitomi Watanabe, Tsukuba, JP;
Takeru Yamakawa, Tsukuba, JP;
Lihu Yang, Edison, NJ (US);
MSD K.K., Tokyo, JP;
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The invention relates to a compound of a general formula (I): wherein Ar1 represents a group formed from an aromatic ring selected from a group consisting of benzene, pyrazole, isoxazole, pyridine, indole, 1H-indazole, 1H-furo[2,3-c]pyrazole, 1H-thieno[2,3-c]pyrazole, benzimidazole, 1,2-benzisoxazole, imidazo[1,2-a]pyridine, imidazo[1,5-a]pyridine and 1H-pyrazolo[3,4-a]pyridine, having Ar2, and optionally having one or two or more substituents selected from R3; R1 and R2 each independently represent a hydrogen atom, a halogen atom, a cyano group, a C2-C6 alkenyl group, a C1-C6 alkoxy group, a C2-C7 alkanoyl group, a C2-C7 alkoxycarbonyl group, an aralkyloxycarbonyl group, a carbamoyl-C1-C6 alkoxy group, a carboxy-C2-C6 alkenyl group, or a group of -Q1-N(Ra)-Q2-Rb; or a C1-C6 alkyl group optionally having a substituent; or an aryl or heterocyclic group optionally having a substituent; or a C1-C6 alkyl group or a C2-C6 alkenyl group having the aryl or heterocyclic group; T and U each independently represent a nitrogen atom or a methine group; and V represents an oxygen atom or a sulfur atom. The compound of the invention is useful as therapeutical agents for various ACC-related diseases.