The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2012
Filed:
Sep. 24, 2009
Akira Hatayama, Osaka, JP;
Hiroshi Tsuruta, Osaka, JP;
Yasuo Ochi, Osaka, JP;
Haruo Imawaka, Osaka, JP;
Kazuyuki Ohmoto, Osaka, JP;
Akira Hatayama, Osaka, JP;
Hiroshi Tsuruta, Osaka, JP;
Yasuo Ochi, Osaka, JP;
Haruo Imawaka, Osaka, JP;
Kazuyuki Ohmoto, Osaka, JP;
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Abstract
The present invention relates to a diketohydrazine derivative of formula (I) and a pharmaceutically acceptable salt thereof (the symbols in the formula have the same meaning as described in the specification). The compound of formula (I) has an inhibitory activity against cysteine protease, and it is useful for the treatment of inflammatory diseases, immune diseases, ischemic diseases, respiratory diseases, circulatory diseases, blood diseases, neuronal diseases, hepatic or biliary diseases, osseous or articular diseases, metabolic diseases, etc. And the compound has inhibitory activity against elastase and it is also useful for the treatment of COPD (chronic obstacle pulmonary diseases).