The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 20, 2012

Filed:

Mar. 27, 2008
Applicants:

Shelley Allen, Loveland, CO (US);

Julie Marie Greschuk, Erie, CO (US);

Nicholas C. Kallan, Boulder, CO (US);

Fredrik P. Marmsäter, Boulder, CO (US);

Mark C. Munson, Louisville, CO (US);

James P. Rizzi, Longmont, CO (US);

John E. Robinson, Commerce City, CO (US);

Stephen T. Schlachter, Boulder, CO (US);

George T. Topalov, Superior, CO (US);

Qian Zhao, Superior, CO (US);

Joseph P. Lyssikatos, Piedmont, CA (US);

Inventors:

Shelley Allen, Loveland, CO (US);

Julie Marie Greschuk, Erie, CO (US);

Nicholas C. Kallan, Boulder, CO (US);

Fredrik P. Marmsäter, Boulder, CO (US);

Mark C. Munson, Louisville, CO (US);

James P. Rizzi, Longmont, CO (US);

John E. Robinson, Commerce City, CO (US);

Stephen T. Schlachter, Boulder, CO (US);

George T. Topalov, Superior, CO (US);

Qian Zhao, Superior, CO (US);

Joseph P. Lyssikatos, Piedmont, CA (US);

Assignee:

Array BioPharma Inc., Boulder, CO (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5386 (2006.01); A61K 31/437 (2006.01); A61K 31/506 (2006.01); C07D 471/02 (2006.01); C07D 401/14 (2006.01); C07D 498/08 (2006.01); A61P 35/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of Formula I: in which A, B, R, R, R, R, R, RR, Rand Rhave the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of diseases mediated by class 3 and class 5 receptor tyrosine kinases. Particular compounds of this invention have also been found to be inhibitors of Pim-1.


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