The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2012
Filed:
Oct. 24, 2008
Rima F. Kaddurah-daouk, Belmont, MA (US);
Michelle M. Wiest, Knights Landing, CA (US);
Steven M. Watkins, Sacramento, CA (US);
Rebecca Ann Baillie, Woodland, CA (US);
Madhumita Patnaik, Agoura Hills, CA (US);
K. Ranga Rama Krishnan, Chapel Hill, NC (US);
Richard M. Weinshilboum, Rochester, MN (US);
Ronald M. Krauss, Berkeley, CA (US);
Rima F. Kaddurah-Daouk, Belmont, MA (US);
Michelle M. Wiest, Knights Landing, CA (US);
Steven M. Watkins, Sacramento, CA (US);
Rebecca Ann Baillie, Woodland, CA (US);
Madhumita Patnaik, Agoura Hills, CA (US);
K. Ranga Rama Krishnan, Chapel Hill, NC (US);
Richard M. Weinshilboum, Rochester, MN (US);
Ronald M. Krauss, Berkeley, CA (US);
Children's Hospital & Research Center at Oakland, Oakland, CA (US);
Duke University, Durham, NC (US);
Lipomics Technologies, Inc., West Sacramento, CA (US);
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Abstract
The present invention concerns the application of lipidomics to statin treatment for disorders such as cardiovascular disorders. Hence, the invention provides, among other things, a method of correlating a lipid profile with a positive or negative response to a statin treatment regimen by obtaining a lipid profile of a sample from a mammalian subject following commencement of the treatment regimen; and correlating the lipid profile in the sample with a positive or negative response to the treatment regimen. The invention further provides a method of correlating a lipid profile with a positive or negative response to a statin treatment regimen by obtaining a lipid profile of a sample from a mammalian subject before commencement of the treatment regimen; and correlating the lipid profile in the sample with a positive or negative response to the treatment regimen.