The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 13, 2012
Filed:
Mar. 26, 2008
Ali Can, Troy, NY (US);
Michael John Gerdes, Albany, NY (US);
Musodiq Olatayo Bello, Niskayuna, NY (US);
Xiaodong Tao, Niskayuna, NY (US);
Francis Edward Pavan-woolfe, New Haven, CT (US);
Roshni Bhagalia, Ann Arbor, MI (US);
Ali Can, Troy, NY (US);
Michael John Gerdes, Albany, NY (US);
Musodiq Olatayo Bello, Niskayuna, NY (US);
Xiaodong Tao, Niskayuna, NY (US);
Francis Edward Pavan-Woolfe, New Haven, CT (US);
Roshni Bhagalia, Ann Arbor, MI (US);
General Electric Company, Niskayuna, NY (US);
Abstract
Techniques for removing image autoflourescence from fluorescently stained biological images are provided herein. The techniques utilize non-negative matrix factorization that may constrain mixing coefficients to be non-negative. The probability of convergence to local minima is reduced by using smoothness constraints. The non-negative matrix factorization algorithm provides the advantage of removing both dark current and autofluorescence.