The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2012

Filed:

May. 09, 2008
Applicants:

Hassan Pajouhesh, West Vancouver, CA;

Hossein Pajouhesh, Coquitlam, CA;

Yanbing Ding, Richmond, CA;

Jason Tan, Vancouver, CA;

Mike Grimwood, North Vancouver, CA;

Francesco Belardetti, Vancouver, CA;

Ramesh Kaul, Burnaby, CA;

Richard Holland, Vancouver, CA;

Navjot Chahal, Vancouver, CA;

Inventors:

Hassan Pajouhesh, West Vancouver, CA;

Hossein Pajouhesh, Coquitlam, CA;

Yanbing Ding, Richmond, CA;

Jason Tan, Vancouver, CA;

Mike Grimwood, North Vancouver, CA;

Francesco Belardetti, Vancouver, CA;

Ramesh Kaul, Burnaby, CA;

Richard Holland, Vancouver, CA;

Navjot Chahal, Vancouver, CA;

Assignee:

Zalicus Pharmaceuticals, Ltd., Vancouver, British Columbia, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 491/00 (2006.01); C07D 333/00 (2006.01); C07D 333/52 (2006.01); C07D 333/38 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted T-type calcium channel activity are disclosed. Specifically, a series of compounds containing thienopyrimidine or oxoquinazoline derivatives are disclosed of the general formula (1) or formula (2) where X is a linker and Y is an aromatic moiety or N(R5)(R6).


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