The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2012

Filed:

Mar. 23, 2009
Applicants:

Alexander Berthold Hendrik Bakker, Hillegom, NL;

Pauline Marie Louise Meester-rood, Alkmaar, NL;

Adrianus Quirinus Bakker, Abbekerk, NL;

Assignee:

Crucell Holland B.V., Leiden, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); C12P 21/08 (2006.01); A61K 39/395 (2006.01); C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides binding molecules, such as human binding molecules, that bind to and stimulate the human OX40-receptor. The invention also provides nucleic acids encoding such binding molecules. Methods for producing such binding molecules are also provided by the present invention. The binding molecules and nucleic acids are useful in the stimulation of human T-cells and can be used to enhance antigen-specific immune responses.


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