The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2012

Filed:

Nov. 06, 2009
Applicants:

Raymond G. Goodwin, Seattle, WA (US);

Wanwan S. Din, Issaquah, WA (US);

Inventors:

Raymond G. Goodwin, Seattle, WA (US);

Wanwan S. Din, Issaquah, WA (US);

Assignee:

Immunex Corporation, Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/525 (2006.01); C07K 14/475 (2006.01); C07K 14/715 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention discloses a novel interaction between a TNF receptor (TACI) and its interacting ligand (TACI-L). Also disclosed are methods of screening candidate molecules to determine potential antagonists and agonists of the TACI/TACI-L interaction. The use of the antagonists and agonists as therapeutics to treat autoimmune diseases, inflammation, and to inhibit graft vs. host rejections is further disclosed.


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