The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 13, 2012
Filed:
Jul. 20, 2006
Richard Jove, Glendora, CA (US);
Susan E. Minton, Tampa, FL (US);
Carlos A. Muro-cacho, Tampa, FL (US);
Daniel Sullivan, Lutz, FL (US);
Eric Bruce Haura, Tampa, FL (US);
Gerold Bepler, Tierra Verde, FL (US);
Richard Jove, Glendora, CA (US);
Susan E. Minton, Tampa, FL (US);
Carlos A. Muro-Cacho, Tampa, FL (US);
Daniel Sullivan, Lutz, FL (US);
Eric Bruce Haura, Tampa, FL (US);
Gerold Bepler, Tierra Verde, FL (US);
University of South Florida, Tampa, FL (US);
Abstract
Methods are provided for predicting responsiveness of cancer cells to chemotherapy by measuring the level of phosphorylated Stat or the level of expression of Survivin in a cancer and comparing the level in the cancer cell to the respective level in a control. Also provided are methods of selecting a chemotherapeutic treatment for a subject diagnosed with cancer by measuring the level of phosphorylated Stat or the level of expression of Survivin in a cancer and comparing the level in the cancer cell to the respective level in a control. Kits for performing the methods are also provided. Methods for modulating Survivin-dependent apoptosis in a cancer cell are also disclosed.