The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2012

Filed:

Nov. 21, 2008
Applicants:

Geert-jan Boons, Athens, GA (US);

Jun Guo, Athens, GA (US);

Xinghai Ning, Athens, GA (US);

Margaretha Wolfert, Athens, GA (US);

Inventors:

Geert-Jan Boons, Athens, GA (US);

Jun Guo, Athens, GA (US);

Xinghai Ning, Athens, GA (US);

Margaretha Wolfert, Athens, GA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 31/4192 (2006.01); A61K 31/423 (2006.01); A61K 31/4245 (2006.01); C07C 49/323 (2006.01); C07C 33/34 (2006.01); C07C 211/42 (2006.01); C07C 251/56 (2006.01); C07C 69/96 (2006.01); C07C 271/34 (2006.01); C07C 233/10 (2006.01); C07D 249/16 (2006.01); C07D 261/20 (2006.01); C07D 271/12 (2006.01); C07D 405/06 (2006.01); C12N 11/02 (2006.01); A61P 37/04 (2006.01); C08G 16/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The reaction of 1,3-dipole-functional compounds with alkynes can be used for a wide variety of applications including the immobilization of biomolecules on a substrate.


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