The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 06, 2012

Filed:

Jul. 11, 2011
Applicant:

Bogdan Kazimierz Wilk, New City, NY (US);

Inventor:

Bogdan Kazimierz Wilk, New City, NY (US);

Assignee:

Wyeth LLC, Madison, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 265/12 (2006.01); C07D 207/30 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for preparing cyclic carbamates and thiocarbamates containing cyanopyrrole moieties and of the formula are provided: Z are the same or different and are H, optionally substituted Cto Calkyl, or COR; Ris H, optionally substituted Cto Calkyl, optionally substituted Cto Calkoxy, or optionally substituted Cto Caminoalkyl; Q are the same or different and are H, OH, NH, CN, halogen, optionally substituted Cto Calkyl, optionally substituted Cto Calkenyl, optionally substituted Cto Calkynyl, optionally substituted Cto Calkoxy, optionally substituted Cto Caminoalkyl, or COR; and Ris H, optionally substituted Cto Calkyl, optionally substituted Cto Calkoxy, or optionally substituted Cto Caminoalkyl. Compounds including 2-amino-5-(5-cyano--methyl-1H-pyrrol-2-yl) benzoicacid methyl ester, 5-[4-amino-3-(1-hydroxy-1-methyl-ethyl)-phenyl]-1-methyl-1H-pyrrole-2-carbonitrile, and 2-amino-5-(5-cyano--methyl-1H-pyrrol-2-yl)-phenyl-ethanone, or pharmaceutically acceptable salts thereof, and the uses thereof are also provided.


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