The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8129421 B1

PDF
Full Text
Expired
Date of Patent:
Mar. 06, 2012

Filed:

Jun. 16, 2008
Applicants:

Radek Melnicky, Sternberk, CZ;

Pavel Hradil, Hlusovice, CZ;

Lubomir Kvapil, Slatinice, CZ;

Martin Grepl, Hlusovice, CZ;

Petr Slezar, Olomoue, CZ;

Inventors:

Radek Melnicky, Sternberk, CZ;

Pavel Hradil, Hlusovice, CZ;

Lubomir Kvapil, Slatinice, CZ;

Martin Grepl, Hlusovice, CZ;

Petr Slezar, Olomoue, CZ;

Assignee:

Farmak, A S, Olomouc, CZ;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/41 (2006.01); C07D 249/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for preparing 4-[3,5-bis(2-hydroxyphenyl )-[1,2,4]triazol-1-yl]benzoic acid of formula (I) by reaction of 2-(2-hydroxyphenyl)benz[e][1,3]oxazin-4-one of formula (II) with 4-hydrazinobenzoic acid of formula (III) in an organic acid or in a mixture of an organic acid and an organic solvent.


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