The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 06, 2012

Filed:

Jun. 23, 2006
Applicants:

Ralph Calabria, East Brunswick, NJ (US);

Yu Cheng, Harleysville, PA (US);

Russell R. Ferlita, Westfield, NJ (US);

Ashkan Kamali, West Conshohocken, PA (US);

Jerry A. Murry, Jersey City, NJ (US);

David Mathre, Skillman, NJ (US);

Andrey V. Peresypkin, Cranford, NJ (US);

Karen Thompson, Lansdale, PA (US);

Jian Wang, Neshanic Station, NJ (US);

Robert M. Wenslow, Cream Ridge, NJ (US);

Inventors:

Ralph Calabria, East Brunswick, NJ (US);

Yu Cheng, Harleysville, PA (US);

Russell R. Ferlita, Westfield, NJ (US);

Ashkan Kamali, West Conshohocken, PA (US);

Jerry A. Murry, Jersey City, NJ (US);

David Mathre, Skillman, NJ (US);

Andrey V. Peresypkin, Cranford, NJ (US);

Karen Thompson, Lansdale, PA (US);

Jian Wang, Neshanic Station, NJ (US);

Robert M. Wenslow, Cream Ridge, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); C07D 401/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a process for producing N-{(1S)-1-[2-(1-{[(3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl]carbonyl}piperidin-4-yl)-5-chlorophenyl]ethyl}acetamide, and novel crystalline salts, hydrates, solvates, and polymorphic forms thereof.


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