The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 06, 2012

Filed:

Dec. 28, 2006
Applicants:

Takeru Ehara, Tsukuba, JP;

Philipp Grosche, Inzlingen, DE;

Osamu Irie, Tsukuba, JP;

Yuki Iwaki, Tsukuba, JP;

Takanori Kanazawa, Tsukuba, JP;

Shimpei Kawakami, Tsukuba, JP;

Kazuhide Konishi, Tsukuba, JP;

Muneto Mogi, Tsukuba, JP;

Masaki Suzuki, Tsukuba, JP;

Fumiaki Yokokawa, Tsukuba, JP;

Inventors:

Takeru Ehara, Tsukuba, JP;

Philipp Grosche, Inzlingen, DE;

Osamu Irie, Tsukuba, JP;

Yuki Iwaki, Tsukuba, JP;

Takanori Kanazawa, Tsukuba, JP;

Shimpei Kawakami, Tsukuba, JP;

Kazuhide Konishi, Tsukuba, JP;

Muneto Mogi, Tsukuba, JP;

Masaki Suzuki, Tsukuba, JP;

Fumiaki Yokokawa, Tsukuba, JP;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); C07D 401/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to 3,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,5-substituted piperidine compound, and/or a method of treatment comprising administering a 3,5-substituted piperidine compound, a method for the manufacture of a 3,5-substituted piperidine compound, and novel intermediates and partial steps for its synthesis. The compounds have the formula I' wherein R1, R2, T, R3 and R4 are as defined in the specification.


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