The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 06, 2012

Filed:

Nov. 12, 2008
Applicants:

Michael Gerard Gallagher, Newhouse, GB;

Craig C. Jamieson, Newhouse, GB;

Amanda Jane Lyons, Newhouse, GB;

John Kinnaird Ferguson Maclean, Newhouse, GB;

Elizabeth Margaret Moir, Newhouse, GB;

Inventors:

Michael Gerard Gallagher, Newhouse, GB;

Craig C. Jamieson, Newhouse, GB;

Amanda Jane Lyons, Newhouse, GB;

John Kinnaird Ferguson Maclean, Newhouse, GB;

Elizabeth Margaret Moir, Newhouse, GB;

Assignee:

MSD Oss B.V., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61K 31/519 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); A61P 25/22 (2006.01); A61P 25/18 (2006.01); A61P 25/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a heterocyclic derivative according to formula I wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising said heterocyclic derivatives and to their use in therapy, for instance in the treatment or prevention of psychiatric diseases where an enhancement of synaptic responses mediated by AMPA receptors is required, including schizophrenia, depression and learning and memory disorders such as Alzheimer's disease.


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