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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8129372 B1

PDFFull Text
Date of Patent:
Mar. 06, 2012

Filed:

Apr. 20, 2009

Compounds having npy y5 receptor antagonistic activity

Applicant:

Masahiro Sakagami, Sapporo, JP;

Inventor:

Masahiro Sakagami, Sapporo, JP;

Assignee:

Shionogi & Co., Ltd., Osaka-shi, JP;

Attorney:

Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.

Primary Examiner:

Sun Jae Loewe

Int. Cl.
CPC ...
A61K 31/536 (2006.01); A61K 31/4439 (2006.01); A61K 31/40 (2006.01); A61K 31/4174 (2006.01); A61K 31/415 (2006.01); A61K 31/4196 (2006.01); A61K 31/404 (2006.01); A61K 31/506 (2006.01); A61K 31/497 (2006.01); A61K 31/427 (2006.01); A61K 31/422 (2006.01); A61K 31/5377 (2006.01); A61K 31/519 (2006.01); A61K 31/4985 (2006.01); A61K 31/444 (2006.01); C07D 401/10 (2006.01); C07D 401/14 (2006.01); C07D 207/335 (2006.01); C07D 233/64 (2006.01); C07D 231/12 (2006.01); C07D 249/08 (2006.01); C07D 209/14 (2006.01); C07D 403/10 (2006.01); C07D 417/10 (2006.01); C07D 413/10 (2006.01); A61P 3/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides a compound of the formula (I): a pharmaceutically acceptable salt or solvate thereof,whereinRis substituted or unsubstituted alkyl or the like,Ris hydrogen or substituted or unsubstituted alkyl,Ring A is monocyclic or bicyclic aromatic heterocycle,Ris substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl or substituted or unsubstituted heterocycle,Ris halogen, cyano, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl or the like,m is an integer between 0 and 2,n is an integer between 0 and 5,R is halogen, oxo, cyano, nitro, substituted or unsubstituted alkyl or the like, andp is an integer between 0 and 2as novel compounds having NPY Y5 antagonistic activity.

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