The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2012
Filed:
Mar. 30, 2007
Takashi Imai, Chiba, JP;
Mayumi Iwakawa, Chiba, JP;
Hitoshi Shibuya, Chiba, JP;
Masahiko Miura, Chiba, JP;
Ryoichi Yoshimura, Chiba, JP;
Hiroshi Watanabe, Chiba, JP;
Takashi Imai, Chiba, JP;
Mayumi Iwakawa, Chiba, JP;
Hitoshi Shibuya, Chiba, JP;
Masahiko Miura, Chiba, JP;
Ryoichi Yoshimura, Chiba, JP;
Hiroshi Watanabe, Chiba, JP;
National Institute of Radiological Sciences, Chiba-Shi, Chiba, JP;
Abstract
A method for objectively predicting possibility of metastasis to a cervical lymph node in an early stage for an individual case diagnosed as an oral cavity cancer, and a diagnosis kit to be used in the prediction are provided. The method includes a step of assaying expression amounts of metastasis prediction genes in which the expression amounts are changed between a metastasis group and a non-metastasis group, with respect to a sample collected from a primary legion of the oral cavity cancer. Further, the method includes a step of predicting the possibility of the metastasis by comparing the expression amounts of the metastasis gene group with the expression amounts of the metastasis prediction genes in a metastasis group and/or a non-metastasis group. Herein, the metastasis prediction gene group includes two genes MSR1 (NM_138716.1) and RET (M31213.1).