The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8128935 B1

PDF
Full Text
Expired
Date of Patent:
Mar. 06, 2012

Filed:

Jun. 11, 2003
Applicants:

Helmut Fiebig, Schwarzenbek, DE;

Andreas Nandy, Hamburg, DE;

Roland Suck, Hamburg, DE;

Oliver Cromwell, Wentorf, DE;

Arnd Petersen, Bad Segeberg, DE;

Wolf-meinhard Becker, Mozen, DE;

Inventors:

Helmut Fiebig, Schwarzenbek, DE;

Andreas Nandy, Hamburg, DE;

Roland Suck, Hamburg, DE;

Oliver Cromwell, Wentorf, DE;

Arnd Petersen, Bad Segeberg, DE;

Wolf-Meinhard Becker, Mozen, DE;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 39/35 (2006.01); A61K 39/36 (2006.01); A01N 37/18 (2006.01); C07K 1/00 (2006.01); C07K 14/00 (2006.01); C07K 17/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to the provision of the genetic sequence of the major grass pollen allergen Phl p 4. The invention also covers fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilised for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for the in vitro and in vivo diagnosis of pollen allergies.


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