The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2012
Filed:
Oct. 20, 2006
Elena Ranieri, Bari, IT;
Michele Battaglia, Bari, IT;
Herr Wolfgang, Mainz, DE;
Loreto Gesualdo, Altamura, IT;
Elena Ranieri, Bari, IT;
Michele Battaglia, Bari, IT;
Herr Wolfgang, Mainz, DE;
Loreto Gesualdo, Altamura, IT;
Universita' Degli Studi Di Bari, Bari, IT;
Universita' Degli Studi Di Foggia, Foggia, IT;
Abstract
The present invention relates to a renal carcinoma cell line capable of activating the immune system in an antigen-specific manner. According to a further aspect, the invention also includes derivatives of the cell line that maintain said activation capacity. The invention also comprises a method for targeting and activating immune system cells against cells of clear cell renal carcinoma. Said method comprises the co-incubation of isolated immune system cells (dendritic cells, CD4+, CD8+ lymphocytes etc.) with cells of the RCC BA85#21 line in accordance with the invention in a suitable culture medium, for a time sufficient to obtain antigen specific cells.