The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2012
Filed:
Nov. 17, 2009
Jeffrey W. Smith, La Jolla, CA (US);
Fumiko Axelrod, La Jolla, CA (US);
Steven J. Kridel, La Jolla, CA (US);
Daniel Romo, College Station, TX (US);
Vikram Purohit, College Station, TX (US);
Gil MA, College Station, TX (US);
Jeffrey W. Smith, La Jolla, CA (US);
Fumiko Axelrod, La Jolla, CA (US);
Steven J. Kridel, La Jolla, CA (US);
Daniel Romo, College Station, TX (US);
Vikram Purohit, College Station, TX (US);
Gil Ma, College Station, TX (US);
Sanford-Burnham Medical Research Institute, La Jolla, CA (US);
Abstract
The present invention features methods of treating a cancer in a subject by administering an effective amount of a beta-lactone to the subject. The invention also features methods of inhibiting angiogenesis in a subject by administering an effective amount of an inhibitor of fatty acid synthase to the subject. These methods can be used to treat a variety of cancers and other diseases and conditions. The invention also features methods of identifying beta-lactones and other compounds that can be used in the methods of the invention for the treatment of tumors, inhibition of angiogenesis, and the treatment of diseases and conditions that involve pathological angiogenesis. The invention also features methods of synthesizing beta-lactones and features novel beta-lactone compounds.