The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2012
Filed:
Apr. 07, 2008
Robert J. Devita, Westfield, NJ (US);
Sander G. Mills, Scotch Plains, NJ (US);
Jinlong Jiang, Scotch Plains, NJ (US);
Andrew J. Kassick, Scotch Plains, NJ (US);
Jianming Bao, Princeton, NJ (US);
Robert J. DeVita, Westfield, NJ (US);
Sander G. Mills, Scotch Plains, NJ (US);
Jinlong Jiang, Scotch Plains, NJ (US);
Andrew J. Kassick, Scotch Plains, NJ (US);
Jianming Bao, Princeton, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention is directed to certain hydroxymethyl ether hydroisoindoline compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, urinary incontinence, LUTS, depression, and anxiety.