The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2012
Filed:
Sep. 14, 2001
Teruo Yamamori, Takarazuka, JP;
Kiyoshi Nagata, Osaka, JP;
Natsuki Ishizuka, Osaka, JP;
Kunio Hayashi, Kadoma, JP;
Teruo Yamamori, Takarazuka, JP;
Kiyoshi Nagata, Osaka, JP;
Natsuki Ishizuka, Osaka, JP;
Kunio Hayashi, Kadoma, JP;
Shionogi & Co., Ltd., Osaka, JP;
Abstract
Compounds having an activity to enhance the expression of apoAI are provided. Compounds of formula (I): in which Arand Arare independently a phenyl, naphthyl, or monocyclic or bicyclic aromatic heterocyclic group, which may be optionally substituted; —X— is —N═CZ—, —CY═CZ—, —CYY—CHZ—, —S—, —O—, or the like; Y, Y, Y, Zand Zare independently a hydrogen, a halogen, a lower alkyl, a phenyl, or the like; Zand Zmay be independently a linker group that may combine with Arand Arto form a condensed ring; m is 0 or 1, and n is 0 to 2; a prodrug thereof, a pharmaceutically acceptable salt or solvate thereof; are disclosed.