The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2012

Filed:

Sep. 17, 2008
Applicants:

Hans-jochen Lang, Frankfurt am Main, DE;

John Weston, Frankfurt am Main, DE;

Uwe Heinelt, Frankfurt am Main, DE;

Inventors:

Hans-Jochen Lang, Frankfurt am Main, DE;

John Weston, Frankfurt am Main, DE;

Uwe Heinelt, Frankfurt am Main, DE;

Assignee:

Sanofi-Aventis, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 217/22 (2006.01); A61K 31/47 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds useful in the prevention or treatment of various disorders such as acute or chronic renal failure, for impairments of biliary function, for respiratory impairments such as snoring or sleep apneas or for stroke, and pharmaceutical compositions comprising them. More specifically, the compounds of the present invention comprises substituted 1-amino-4-phenyl-dihydroisoquinolines and their derivatives of formula I: Wherein the substituents R1-R11 are more specifically defined hereinbelow. The claimed compounds of the present invention also include their pharmaceutically acceptable salts and trifluoroacetates thereof as well as methods for their preparation and pharmaceutical delivery systems thereof.


Find Patent Forward Citations

Loading…