The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2012
Filed:
Jul. 14, 2008
Alan Bradley Fulp, Williow Spring, NC (US);
Matthew Scott Johnson, Durham, NC (US);
Christopher John Markworth, Durham, NC (US);
Brian Edward Marron, Durham, NC (US);
Darrick Conway Seconi, Cary, NC (US);
Christopher William West, Cary, NC (US);
Xiaodong Wang, Chapel Hill, NC (US);
Shulan Zhou, Chapel Hill, NC (US);
Alan Bradley Fulp, Williow Spring, NC (US);
Matthew Scott Johnson, Durham, NC (US);
Christopher John Markworth, Durham, NC (US);
Brian Edward Marron, Durham, NC (US);
Darrick Conway Seconi, Cary, NC (US);
Christopher William West, Cary, NC (US);
Xiaodong Wang, Chapel Hill, NC (US);
Shulan Zhou, Chapel Hill, NC (US);
Icagen Inc., Durham, NC (US);
Abstract
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted sulfonamides, compositions comprising these compounds, as well as methods of using these compounds or compositions in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.