The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2012

Filed:

Dec. 18, 2003
Applicants:

Werner Seeger, Giessen, DE;

Andreas Günther, Giessen, DE;

Clemens Ruppert, Giessen, DE;

Philipp Markart, Giessen, DE;

Viktor Magdolen, Munich, DE;

Timothy E. Weaver, Morrow, OH (US);

Inventors:

Werner Seeger, Giessen, DE;

Andreas Günther, Giessen, DE;

Clemens Ruppert, Giessen, DE;

Philipp Markart, Giessen, DE;

Viktor Magdolen, Munich, DE;

Timothy E. Weaver, Morrow, OH (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); C07K 14/435 (2006.01); C07H 21/04 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to recombinant chimeric proteins comprising a surfactant protein precursor N-terminally fused to a plasminogen activator or comprising a mature surfactant protein N-terminally or C-terminally fused to a plasminogen activator. The invention is also directed to the corresponding nucleic acid molecules encoding such fusion proteins as well as to a method for their production. The invention further refers to a pharmaceutical composition comprising such a fusion protein and to pharmacological uses of an inventive fusion protein for the prevention and/or treatment of inflammatory and interstitial lung diseases.


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