The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2012

Filed:

Jul. 30, 2004
Applicants:

Sutisak Kitareewan, Ordford, NH (US);

Roger Sloboda, Hanover, NH (US);

Ethan Dmitrovsky, Hanover, NH (US);

Inventors:

Sutisak Kitareewan, Ordford, NH (US);

Roger Sloboda, Hanover, NH (US);

Ethan Dmitrovsky, Hanover, NH (US);

Assignee:

Trustees of Dartmouth College, Hanover, NH (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/37 (2006.01); C12Q 1/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compositions for destabilizing lysosomes to increase the degradation of oncogenic or aberrant proteins for the prevention or treatment of disease. Methods for identifying agents which destabilize lysosomes are also provided as are agents identified in accordance with the screening method.


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