The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2012
Filed:
May. 07, 2009
Sergey V. Sheleg, Scottsdale, AZ (US);
Hugh Leroy Hixon, Jr., Scottsdale, AZ (US);
Sergei A. Svarovsky, Scottsdale, AZ (US);
Bruce Cohen, Scottsdale, AZ (US);
Sergey V. Sheleg, Scottsdale, AZ (US);
Hugh LeRoy Hixon, Jr., Scottsdale, AZ (US);
Sergei A. Svarovsky, Scottsdale, AZ (US);
Bruce Cohen, Scottsdale, AZ (US);
Other;
Abstract
A method for hypothermic preservation of biological tissue for later recovery to a viable state includes flushing the biological tissue with a gas mixture of sulfur hexafluoride or xenon and oxygen. The sulfur hexafluoride or xenon is in a concentration in the mixture between about 75 mole percent to 95 mole percent. The method includes pressurizing the biological tissue, preferably isothermically, with the mixture to a pressure that will form clathrates inside the biological tissue at a desired storage temperature in a range of about +1° C. to about +5° C. The method includes a step of cooling the biological tissue, preferably isobarically, to the desired storage temperature. Optional steps for further cooling to no colder than about −20° C. and for depressurization are provided as well as steps for recovering the hypothermically preserved biological tissue to a viable state, preferably using a recovery gas mixture.